Lendület Laboratory of Neuronal Signaling
MTA Research Institute of Experimental Medicine

PATTERN Group
Department of Theory
MTA Wigner Research Centre for Physics

 

Contact

address     13-9, 29-33 Konkoly Thege St, Budapest, 1121
email         ujfalussyn.obalazs . benedekt@mwigner.emta.!hu
phone       +36-1-392 2222 / 3257

My primary research interest is to understand how cortical neurons are adapted to their environment i.e., the circuit they are embedded: the computation it performs and the activities of the other neurons. In my research I combine ideas from systems neuroscience and machine learning with single neuron modelling and data analysis to characterise the spatio-temporal distribution of natural activity patterns in neuronal populations and to capture the response of single neurons to stimuli sampled from this distribution. This approach has the potential to reveal the contribution of specific single neuron properties to the computation performed by the network.

Selected publications

Balázs B Ujfalussy, Judit K Makara, Tiago Branco, Máté Lengyel: Dendritic nonlinearities are tuned for efficient spike-based computations in cortical circuits.  eLife 2015;4:e10056

Balazs B. Ujfalussy, Máté Lengyel: Active dendrites: adaptation to spike-based commu- nication. in Advances in Neural Information Processing Systems 24 edited by J. Shawe- Taylor and R.S. Zemel and P. Bartlett and F. Pereira and K.Q. Weinberger (2011)

Balázs B. Ujfalussy, T Kiss, P. Érdi: Parallel computational subunits in dentate granule cells generate multiple place fields. PLoS Comput Biol 5(9):e1000500 (2009)

D. Samu, P. Erős, Balázs B. Ujfalussy, T Kiss: Robust path integration in the entorhinal grid cell system with hippocampal feed-back. Biological Cybernetics 101(1):19-34 (2009)

Balázs B. Ujfalussy, T. Kiss, G. Orbán, WE Hoffmann, P. Érdi, M. Hajós: Pharmacological and computational analysis of alpha-subunit preferential GABA-A positive allosteric modulators on the rat septo-hippocampal activity. Neuropharmacology – 52(3):733-43 (2007)

Balázs B. Ujfalussy and T. Kiss: How do glutamatergic and GABAergic cells contribute to syn- chronization in the medial septum? Journal of Computational Neuroscience 21,(3):343- 357 (2006)

Balázs Ujfalussy earned his PhD from Eötvös University under the supervision of Péter Érdi and Tamás Kiss studying the formation of spatial representations in the hippocampus. In 2011 he was awarded a Marie Curie Posdoctoral Fellowship and joined the group of  Máté Lengyel at the Computational and Biological Learning Lab at the University of Cambridge to study the role of nonlinear dendrites in spiking networks. In 2014 he worked with in the MRC Laboratory of Molecular Biology (Cambridge, UK) with Tiago Branco where he modelled the response of cortical neurons to synaptic stimuli with complex spatio-temporal structure. He is currently an MTA postdoctoral fellow in the Lendület Laboratory of Neuronal Signaling with Judit Makara and joined the efforts of the PATTERN group in 2015.